Trinity Health's primary hospital campus, Trinity Hospital, is accredited by the Joint Commission and is the region's tertiary referral hospital.  Trinity Hospital is a Level II Trauma Center with cardiac, neuro, ortho, and other specialty and surgical services offered around the clock. First Response emergency transportation services include ground ambulances, a Minot-based helicopter serving a 150 mile radius and fixed-wing aircraft services in both Minot and Williston, which provide transport for patients anywhere in the United States.

Trinity Hospital is a 251-bed hospital offering a full compliment of medical services.  Patients are often referred from smaller hospitals for major operations, consultations with sub-specialists, and when sophisticated intensive care facilities or advanced diagnostic testing is required.