Trinity CancerCare Center: Cancer Trials

  • Clinical Trials in CancerCare:

    Brain Cancer: (or metastatic disease to the brain)

    • Currently no open trials.

    Breast Cancer:

    • NSABP B-43: A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
    • NSABP B-47: A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women With Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer
    • NCIC MA.32: A Phase III Randomized Trial of Metformin vs. Placebo on Recurrence and Survival in Early Stage Breast Cancer
    • CCCWF 97609: Impact of Genomics and Exposures on Disparities in Breast Cancer Radiosensitivity
    • ECOG 2108: A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer

    Colon or Rectal Cancer:

    • N08CB: A Phase III Randomized, Placebo-Controlled, Double-Blind Study of Intravenous Calcium/Magnesium in Two Different Versions to Prevent Oxaliplatin-Induced Sensory Neuropathy
    • NSABP P-5: Statin Polyp Prevention Trial in Patients with Resected Colon Cancer
    • Myriad Genetics: A Prospective, Randomized, Open-Label Trial Comparing OnDose AUC Optimized 5-FU Based Administration vs. Standard Body Surface Area Dosing in Metastatic Colorectal Cancer Patients treated with mFOLFOX6

    Esophageal Cancer

    • RTOG 0436: A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients with Esophageal Cancer Who Are Treated Without Surgery
    • RTOG 1010: A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of Her2-Overexpressing Esophageal Adenocarcinoma

    Lung Cancer:

    • CALGB 30610: Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer Also Receiving Cisplatin and Etoposide
    • CALGB 30801: A Randomized Phase III Double Blind Trial Evaluating Selective COX-2 Inhibition in COX-2 Expressing Advanced Non-Small Cell Lung Cancer
    • SWOG 0819: A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab With or Without Concurrent Cetuximab in Patients With Advanced Non-Small Cell Lung Cancer
    • RTOG 0937: Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone to Prophylactic Cranial Irradiation and Consolidative Extra-Cranial Irradiation for Extensive Disease Small Cell Lung Cancer
    • ECOG 5508: Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC
    • RTOG 1012: Phase II Randomized Trial of Prophylactic Manuka Honey for the Reduction of Chemoradiation Therapy Induced Esophagitis-Related Pain During the Treatment of Lung Cancer

    Multiple Myeloma:

    • Currently no open trials.

    Prostate Cancer:

    • RTOG 0815: A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer

    Cancer with Bone Metastases:

    • Currently no open trials.
  • Accreditation

    Accredited by the American College of Surgeons Commission on Cancer, Trinity�s CancerCare Center services are linked with one of the nation�s leading cancer research organization for the purpose of conducting clinical trial.

    Through Radiation Therapy Oncology Group (RTOG) and Cancer Trials Support Unit (CTSU), trials can be accessed locally that are available worldwide. These trials link Trinity CancerCare patients to physicians and patients in other cancer care centers such as Mayo Clinic and MD Anderson Cancer Care Center.

    Clinical trials assure that each patient is receiving the most advanced care possible through an exchange of treatment information. This allows patients to remain close to home and their family support system while receiving cancer care.

    In addition, Trinity CancerCare Center has an active and functional Tumor Registry.

    A Tumor Registry is a system that records all the types of cancers patients are diagnosed with along with their treatments so that data-driven, evidence-based cancer prevention and control programs can be implemented to reduce cancer morbidity and mortality.

  • Learn More:

    For more information on specific types of cancer, treatment and symptoms, visit the American Cancer Society.

  • Contact Information for Cancer Research Trials:

    Nadia Smetana BSN, RN, CCRP
    Oncology Research Coordinator
    (701) 857-3174

    or

    Loretta Porter, RN, BSN
    Cancer Research Nurse
    (701) 857-3174